Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045493 | 0.68 | METAP1 (0.36) | ALDH1A1 | |
| SCHEMBL12553901 | 0.65 | — | — | |
| SCHEMBL472480 | 0.61 | ALDH1A1 (0.72) | TSHRGAAALDH1A1 | |
| SCHEMBL7646672 | 0.60 | ALDH1A1 (0.43) | TSHRGAAALDH1A1 | |
| SCHEMBL17294189 | 0.59 | ALDH1A1 (0.69) | TSHRGAAALDH1A1 | |
| SCHEMBL11046040 | 0.59 | MEN1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL9402148 | 0.59 | GAA (0.45) | RGS12TSHRGAAALDH1A1 | |
| SCHEMBL24322914 | 0.58 | ALDH1A1 (0.30) | TSHRALDH1A1 | |
| SCHEMBL22787169 | 0.58 | TDP1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL16511128 | 0.58 | ALDH1A1 (0.45) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136804-A1 | PYRIMIDINE DERIVATIVES FOR USE AS ANTIBIOTICS | ASTON UNIVERSITY (GB) | 2010-12-02 | — | — | WO | disclosed |