SCHEMBL472480

SCHEMBL472480

C=CCC1C(=O)NC(=O)NC1=O

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
MAPT P10636 3/20 0.47
HPGD P15428 3/20 0.37
POLB P06746 1/20 0.37
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 1/20 0.32
MMP9 P14780 1/20 0.31
LMNA P02545 1/20 0.31
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17294189 0.98 ALDH1A1 (0.69) ALDH1A1MAPTHPGDPOLBHSD17B10
SCHEMBL2143425 0.77 ALDH1A1 (0.50) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL16511128 0.77 ALDH1A1 (0.45) ALDH1A1MAPTHPGDHSD17B10TSHR
Formaldehyde SCHEMBL8154204 0.76 ALDH1A1 (0.48) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL17651926 0.74 ALDH1A1 (0.68) ALDH1A1MAPTHPGDPOLBKDM4E
SCHEMBL16511063 0.74 ALDH1A1 (0.44) ALDH1A1MAPTHPGDHSD17B10TSHR
SCHEMBL11664426 0.72 ALDH1A1 (0.38) ALDH1A1MAPTHSD17B10TSHRKDM4E
SCHEMBL7646672 0.71 ALDH1A1 (0.43) ALDH1A1MAPTHPGDPOLBHSD17B10
SCHEMBL22790519 0.71 ALDH1A1 (0.52) ALDH1A1CES2
SCHEMBL9280423 0.70 ALDH1A1 (0.52) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US claimed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP claimed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO claimed
US-20130309595-A1 ELECTROCATALYSTS FOR FUEL CELLS DREXEL UNIVERSITY (US) 2013-11-21 US claimed
US-20100285392-A1 ELECTROCATALYSTS FOR FUEL CELLS DREXEL UNIVERSITY (US) 2010-11-11 US claimed
WO-2009045879-A2 ELECTROCATALYSTS FOR FUEL CELLS DREXEL UNIVERSITY (US) 2009-04-09 WO claimed
EP-1387659-B1 INITIATOR SYSTEM FOR ACID DENTAL FORMULATIONS 3M ESPE AG (DE) 2008-05-07 EP claimed
US-6472453-B2 MOLDING MATERIALS OF AN ADDITION POLYMERIZABLE MIXTURE OF A POLYMER, A POLYMER CATALYST AND A COMPOUND OF AN ACRYLIC ESTER OF A HYDROXYALKANAL OR A HYDROXYALKYL KETONE; INCREASED SOLUBILITY; DECREASED VOLATILITY; DENTISTRY; FINGERNAILS APPLIED DENTAL SCIENCES, INC. 2002-10-29 US claimed
US-20020086915-A1 Compositions for making an artificial prosthesis DISCUS DENTAL, LLC 2002-07-04 US claimed
US-20010056133-A1 Curable compositions with antimicrobial properties MONTGOMERY R ERIC (US) 2001-12-27 US claimed
EP-1056430-A2 CURABLE COMPOSITIONS WITH ANTIMICROBIAL PROPERTIES Oraceutical, LLC (US) 2000-12-06 EP claimed
WO-1999042080-A2 CURABLE COMPOSITIONS WITH ANTIMICROBIAL PROPERTIES ORACEUTICAL, LLC (US) 1999-08-26 WO claimed
US-4534839-A CAMPHORQUINONE SENSITIZER AND ALKYL-AND ARYL BARB TURIC ACID REDUCING AGENTS KULZER & CO. GMBH (DE) 1985-08-13 US claimed
US-4382983-A PARTIALLY HYDROLYZED SILOXANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-10 US claimed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
US-12440426-B2 Dental product with reduced extrusion forces SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-10-14 US disclosed
US-20250255785-A1 Dental Product with Reduced Extrusion Forces SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-08-14 US disclosed
EP-0351091-A2 Vulcanizable epoxy group-containing elastomer compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-17 EP disclosed
WO-1989006666-A1 ADHESION PROMOTERS FOR THIOLENE ADHESIVE FORMULATIONS LOCTITE CORPORATION (US) 1989-07-27 WO disclosed
US-4534839-A CAMPHORQUINONE SENSITIZER AND ALKYL-AND ARYL BARB TURIC ACID REDUCING AGENTS KULZER & CO. GMBH (DE) 1985-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086915-A1 Compositions for making an artificial prosthesis PHOSPHO1, FAM120A, PDE10A ALDH1A1 4197/4885MAPT 4604/4885HPGD 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.