Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295735 | 0.89 | MCL1 (0.47) | EDNRBEDNRACA12CA1CA2 | |
| SCHEMBL19383271 | 0.84 | PDK2 (0.42) | EDNRBEDNRACA12CA1CA2 | |
| SCHEMBL13045512 | 0.84 | SMN1; SMN2 (0.44) | CA12CA1CA2CA9MCL1 | |
| SCHEMBL28543533 | 0.83 | MCL1 (0.39) | EDNRBEDNRACA12CA1CA2 | |
| SCHEMBL16674520 | 0.81 | MCL1 (0.40) | EDNRBEDNRACA12CA1CA2 | |
| SCHEMBL19383290 | 0.81 | MCL1 (0.40) | EDNRBEDNRACA12CA1CA2 | |
| SCHEMBL18904429 | 0.81 | ALDH1A1 (0.43) | EDNRBEDNRACA12CA1CA2 | |
| SCHEMBL19383278 | 0.81 | MCL1 (0.40) | EDNRBEDNRACA12CA1CA2 | |
| SCHEMBL10057971 | 0.80 | MEN1 (0.50) | EDNRBEDNRA | |
| SCHEMBL10057964 | 0.80 | MEN1 (0.50) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838126-B2 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2010-11-23 | — | — | US | disclosed |
| US-7838126-B2 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2010-11-23 | — | — | US | disclosed |
| US-20070164273-A1 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2007-07-19 | — | — | US | disclosed |
| US-20070164273-A1 | Organic electronic devices | MERCK PATENT GMBH (DE) | 2007-07-19 | — | — | US | disclosed |