SCHEMBL14819863

SCHEMBL14819863

CCc1c(C(N)=O)nn(-c2ccc(N)cc2Cl)c1-c1ccc(C#CCC(C)C)s1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.64
CNR2 P34972 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13045552 0.92 CNR1 (0.74) CNR1CNR2
SCHEMBL13045545 0.82 CNR1 (0.73) CNR1CNR2
SCHEMBL3740252 0.78 CNR1 (1.00) CNR1CNR2
SCHEMBL13079102 0.76 CNR2 (0.54) CNR1CNR2
SCHEMBL13045542 0.72 CNR1 (0.73) CNR1CNR2
SCHEMBL2849541 0.72 CNR1 (0.63) CNR1CNR2
SCHEMBL13045549 0.72 CNR1 (0.74) CNR1CNR2
SCHEMBL13078764 0.72 CNR2 (0.56) CNR1CNR2
SCHEMBL13045539 0.71 CNR1 (0.79) CNR1CNR2
SCHEMBL2850242 0.70 CNR1 (0.63) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2068870-B1 THIOPHENE COMPOUNDS NAT HEALTH RESEARCH INSTITUTES (TW) 2013-03-27 EP disclosed