Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | OAT | P04181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063270 | 0.76 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL9218081 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL9745576 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL13758784 | 0.72 | IDUA (0.36) | SMN1; SMN2 | |
| SCHEMBL17678526 | 0.72 | IDUA (0.36) | SMN1; SMN2 | |
| SCHEMBL2806987 | 0.69 | POLB (0.43) | SMN1; SMN2 | |
| SCHEMBL188282 | 0.69 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL3530476 | 0.69 | SIRT1 (0.41) | SMN1; SMN2 | |
| SCHEMBL2804445 | 0.67 | CYP2C9 (0.48) | SMN1; SMN2 | |
| SCHEMBL3183082 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834033-B2 | Methods for treating cancer using 3-[1,3dioxo-4-benzamidoisoindolin-2-yl]-2,6-dioxo-5-hydroxypiperidine | CELGENE CORPORATION (US) | 2010-11-16 | — | — | US | disclosed |
| US-7834033-B2 | Methods for treating cancer using 3-[1,3dioxo-4-benzamidoisoindolin-2-yl]-2,6-dioxo-5-hydroxypiperidine | CELGENE CORPORATION (US) | 2010-11-16 | — | — | US | disclosed |
| EP-1733726-B1 | Pharmaceutically active isoindoline derivatives | CELGENE CORP (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1341537-B1 | PHARMACEUTICALLY ACTIVE ISOINDOLINE DERIVATIVES | CELGENE CORP (US) | 2007-01-24 | — | — | EP | disclosed |