Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDUA | P35475 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17678526 | 1.00 | IDUA (0.36) | IDUAGUSBSMN1; SMN2LMNAGBA1 | |
| SCHEMBL4063270 | 0.78 | SMN1; SMN2 (0.35) | IDUAGUSBSMN1; SMN2 | |
| SCHEMBL9218081 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL13045595 | 0.72 | GABRR1 (0.36) | SMN1; SMN2 | |
| SCHEMBL9745576 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL2806987 | 0.72 | POLB (0.43) | SMN1; SMN2LMNA | |
| SCHEMBL19215282 | 0.70 | KMT2A (0.40) | IDUAGUSBSMN1; SMN2LMNAGBA1 | |
| SCHEMBL12292959 | 0.68 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL188282 | 0.68 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL17931566 | 0.67 | LMNA (0.44) | LMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563896-B2 | Process of obtaining type II dehydroquinase enzyme inhibitors and precursors thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2009-07-21 | — | — | US | disclosed |
| US-20070185214-A1 | Process of obtaining type II dehydroquinase enzyme inhibitors and precursors thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2007-08-09 | — | — | US | disclosed |
| US-20070185214-A1 | Process of obtaining type II dehydroquinase enzyme inhibitors and precursors thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185214-A1 | Process of obtaining type II dehydroquinase enzyme inhibitors and precursors thereof | NQO2, CYP1A2, HPD | IDUA 210/4885GUSB 202/4885SMN1; SMN2 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.