Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901915 | 0.84 | GRM5 (0.46) | GRM5TTRALBVCAM1CA1 | |
| SCHEMBL21927207 | 0.76 | TTR (0.41) | GRM5TTRALBVCAM1MEN1 | |
| SCHEMBL583616 | 0.74 | GRM5 (0.48) | GRM5VCAM1MEN1KMT2A | |
| SCHEMBL11620108 | 0.74 | GRM5 (0.41) | GRM5VCAM1 | |
| SCHEMBL10379441 | 0.71 | ALDH1A1 (0.41) | GRM5VCAM1MEN1KMT2AGPR35 | |
| SCHEMBL11296944 | 0.69 | GRM5 (0.51) | GRM5VCAM1 | |
| SCHEMBL30563178 | 0.69 | GRM5 (0.38) | GRM5VCAM1 | |
| SCHEMBL6177216 | 0.69 | GRM5 (0.38) | GRM5TTRALBVCAM1MEN1 | |
| SCHEMBL30745049 | 0.69 | MEN1 (0.41) | GRM5TTRALBVCAM1MEN1 | |
| SCHEMBL30824106 | 0.69 | GRM5 (0.38) | GRM5TTRALBVCAM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141805-A1 | HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | disclosed |