Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824106 | 1.00 | GRM5 (0.38) | GRM5VCAM1MEN1KMT2AGLA | |
| SCHEMBL901915 | 0.79 | GRM5 (0.46) | GRM5VCAM1MEN1KMT2ATTR | |
| SCHEMBL24156964 | 0.77 | MEN1 (0.36) | MEN1KMT2AHTTTTRALB | |
| SCHEMBL30253314 | 0.77 | MEN1 (0.36) | MEN1KMT2AHTTTTRALB | |
| SCHEMBL583616 | 0.74 | GRM5 (0.48) | GRM5VCAM1MEN1KMT2AKDM4E | |
| SCHEMBL1532341 | 0.73 | TRPM8 (0.41) | MEN1KMT2ATSHRHTTMAPT | |
| SCHEMBL11620108 | 0.69 | GRM5 (0.41) | GRM5VCAM1HTTL3MBTL1 | |
| SCHEMBL7088876 | 0.69 | MAPT (0.39) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL13045682 | 0.69 | GRM5 (0.41) | GRM5VCAM1MEN1KMT2ATTR | |
| SCHEMBL11296944 | 0.69 | GRM5 (0.51) | GRM5VCAM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343056-A | Pyridopyrrole derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-1427725-B1 | PYRAZOLYL-SUBSTITUTED THIENYLOXYPYRIDINES | BASF AG (DE) | 2005-03-23 | — | — | EP | disclosed |
| US-20040235667-A1 | Pyrazolyl-substituted thienyloxypyridines | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-1427725-A1 | PYRAZOLYL-SUBSTITUTED THIENYLOXYPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003022843-A1 | PYRAZOLYL-SUBSTITUTED THIENYLOXYPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235667-A1 | Pyrazolyl-substituted thienyloxypyridines | HDHD5, CBR3, KCNH3 | GRM5 2697/4885VCAM1 4556/4885MEN1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.