Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721709 | 0.94 | FFAR1 (0.46) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL10291390 | 0.89 | FFAR1 (0.38) | FFAR1PPARGPPARAPPARDPDCD1 | |
| SCHEMBL13046592 | 0.88 | FFAR1 (0.40) | FFAR1PPARGPPARAPPARDPDCD1 | |
| SCHEMBL3717530 | 0.87 | FFAR1 (0.35) | FFAR1PDCD1CD274 | |
| SCHEMBL1708219 | 0.82 | FFAR1 (0.46) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL13048415 | 0.79 | FFAR1 (0.42) | FFAR1PPARGPPARAPPARDPDCD1 | |
| SCHEMBL1708201 | 0.79 | PDCD1 (0.33) | PDCD1CD274 | |
| SCHEMBL10291219 | 0.78 | FFAR1 (0.40) | FFAR1PPARGPPARDPDCD1CD274 | |
| SCHEMBL10292309 | 0.78 | FFAR1 (0.44) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL13047132 | 0.78 | FFAR1 (0.46) | FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |