Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707845 | 0.88 | PDCD1 (0.33) | PDCD1CD274HDAC6MAPTALDH1A1 | |
| SCHEMBL3717530 | 0.85 | FFAR1 (0.35) | PDCD1CD274HDAC6MAPTALDH1A1 | |
| SCHEMBL13046194 | 0.79 | FFAR1 (0.42) | PDCD1CD274 | |
| SCHEMBL3721709 | 0.78 | FFAR1 (0.46) | — | |
| SCHEMBL1707908 | 0.78 | CD274 (0.41) | PDCD1CD274KMT2A | |
| SCHEMBL1708437 | 0.78 | PDCD1 (0.33) | PDCD1CD274 | |
| SCHEMBL1707949 | 0.77 | PDCD1 (0.36) | PDCD1CD274MAPT | |
| SCHEMBL1708101 | 0.77 | RORC (0.33) | PDCD1CD274 | |
| SCHEMBL1707867 | 0.75 | ALDH1A1 (0.40) | PDCD1CD274MAPTALDH1A1KDM4E | |
| SCHEMBL10291390 | 0.75 | FFAR1 (0.38) | PDCD1CD274HDAC6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |