Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708220 | 0.88 | INSR (0.35) | FFAR1CD274PDCD1P2RX7INSR | |
| SCHEMBL13046194 | 0.87 | FFAR1 (0.42) | FFAR1CD274PDCD1 | |
| SCHEMBL3721709 | 0.87 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL1708201 | 0.85 | PDCD1 (0.33) | CD274PDCD1MAPTHDAC6KDM4E | |
| SCHEMBL10291390 | 0.83 | FFAR1 (0.38) | FFAR1CD274PDCD1P2RX7MAPT | |
| SCHEMBL1708584 | 0.78 | CD274 (0.41) | CD274PDCD1 | |
| SCHEMBL1707921 | 0.78 | CD274 (0.34) | FFAR1CD274PDCD1P2RX7INSR | |
| SCHEMBL1708447 | 0.78 | CD274 (0.33) | FFAR1CD274PDCD1P2RX7INSR | |
| SCHEMBL1708296 | 0.78 | CD274 (0.34) | FFAR1CD274PDCD1P2RX7INSR | |
| SCHEMBL1708348 | 0.77 | GAA (0.39) | CD274MAPTGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |