Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808870 | 0.90 | ACE2 (0.40) | ACE2GABRR1CYP1A2BLMLTA4H | |
| SCHEMBL9069956 | 0.90 | BLM (0.57) | ACE2GABRR1CYP1A2BLMLTA4H | |
| SCHEMBL18159072 | 0.86 | ENPEP (0.35) | ACE2GABRR1CYP1A2BLMENPEP | |
| SCHEMBL13235891 | 0.84 | ACE2 (0.34) | ACE2GABRR1CYP1A2BLM | |
| SCHEMBL14431504 | 0.81 | SLC1A2 (0.44) | — | |
| SCHEMBL6160839 | 0.81 | ACE2 (0.44) | ACE2GABRR1CYP1A2BLMLTA4H | |
| SCHEMBL5539684 | 0.80 | GABRR1 (0.44) | ACE2GABRR1CYP1A2BLMLTA4H | |
| SCHEMBL250969 | 0.80 | GABRR1 (0.44) | ACE2GABRR1CYP1A2BLMLTA4H | |
| SCHEMBL16749901 | 0.80 | GABRR1 (0.44) | ACE2GABRR1CYP1A2BLMLTA4H | |
| SCHEMBL1067868 | 0.80 | BHMT (0.42) | CYP1A2BHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914874-B2 | Composite nanoparticles including a malonic acid derivative | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-13 | — | — | US | disclosed |
| US-20160304775-A1 | COMPOSITE NANOPARTICLES INCLUDING A MALONIC ACID DERIVATIVE | 3M INNOVATIVE PROPERTIES COMPANY | 2016-10-20 | — | — | US | disclosed |
| US-7838584-B2 | Golf ball | BRIDGESTONE SPORTS CO., LTD. (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20080039563-A1 | Golf ball | BRIDGESTONE SPORTS CO., LTD. | 2008-02-14 | — | — | US | disclosed |