Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17878901 | 0.91 | SRC (0.40) | SRCLMNAHTTOXER1CYP1A2 | |
| SCHEMBL1893401 | 0.91 | SRC (0.40) | SRCLMNAHTTOXER1CYP1A2 | |
| SCHEMBL19767756 | 0.87 | SRC (0.38) | SRCLMNAHTTOXER1CYP1A2 | |
| SCHEMBL5414444 | 0.84 | SRC (0.40) | SRCLMNAHTTOXER1CYP1A2 | |
| SCHEMBL17878899 | 0.78 | SRC (0.35) | SRCLMNAHTTOXER1CYP1A2 | |
| SCHEMBL17878896 | 0.77 | TYR (0.36) | SRCLMNAHTTOXER1MAPT | |
| SCHEMBL18480041 | 0.77 | LMNA (0.40) | SRCLMNAHTTOXER1MAPT | |
| SCHEMBL18481326 | 0.75 | OXER1 (0.44) | HTTOXER1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL18175723 | 0.75 | LPL (0.35) | SRCMAPT | |
| SCHEMBL1899113 | 0.75 | ATM (0.37) | SRCLMNACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149261-A1 | POLYMERS CONTAINING STRUCTURAL UNITS THAT COMPRISE ALKYL ALKOXY GROUPS, BLENDS CONTAINING SAID POLYMERS, AND OPTOELECTRONIC DEVICES CONTAINING SAID POLYMERS AND BLENDS | MERCK PATENT GMBH (DE) | 2010-12-29 | — | — | WO | disclosed |