Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.36 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708183 | 0.93 | FFAR1 (0.39) | FFAR1PIK3CAMTOR | |
| SCHEMBL1708213 | 0.91 | MTOR (0.36) | FFAR1PIK3CAMTORALDH1A1MAPT | |
| SCHEMBL10291211 | 0.89 | MTOR (0.34) | PIK3CAMTORALDH1A1MAPTMAPK1 | |
| SCHEMBL1707924 | 0.86 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL1707916 | 0.85 | MTOR (0.36) | PIK3CAMTORALDH1A1MAPTMAPK1 | |
| SCHEMBL1707929 | 0.85 | FFAR1 (0.33) | FFAR1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL1708185 | 0.85 | ALDH1A1 (0.37) | PIK3CAMTORALDH1A1MAPTMAPK1 | |
| SCHEMBL1708215 | 0.84 | ALDH1A1 (0.36) | PIK3CAMTORALDH1A1MAPTMAPK1 | |
| SCHEMBL1708681 | 0.80 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL1708714 | 0.79 | MTOR (0.37) | FFAR1PIK3CAMTORPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |