SCHEMBL1304747

SCHEMBL1304747

Cc1c[c]c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)[c]cc1C

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11330700 1.00 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL21409665 0.78 ALOX15 (0.42) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL7775588 0.78 POLB (0.31)
SCHEMBL2513533 0.74 CYP1A2 (0.34) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL4112873 0.72 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL4679784 0.70 CYP1A2 (0.34) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL5509782 0.66
SCHEMBL5094246 0.64 MAPT (0.35) ALDH1A1ALOX15SMN1; SMN2
SCHEMBL11329694 0.63 TP53 (0.50) TP53ALOX15
SCHEMBL11621524 0.62 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3161063-B1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-06 EP claimed
EP-3387059-B1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-11 EP claimed
US-11142635-B2 Stabilized moisture-curable polymeric compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2021-10-12 US claimed
US-10851258-B2 Stabilized moisture-curable polymeric compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2020-12-01 US claimed
EP-3387059-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS Dow Global Technologies LLC (US) 2018-10-17 EP claimed
US-10100181-B2 Stabilized moisture-curable polymeric compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-16 US claimed
EP-3383943-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS Dow Global Technologies, LLC (US) 2018-10-10 EP claimed
EP-3161062-B1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-02 EP claimed
US-20170210892-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2017-07-27 US claimed
US-20170183477-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2017-06-29 US claimed
WO-2017100049-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-15 WO claimed
WO-2017095571-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-08 WO claimed
EP-3161063-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS Dow Global Technologies LLC (US) 2017-05-03 EP claimed
EP-3161062-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS Dow Global Technologies Llc (US) 2017-05-03 EP claimed
WO-2015200015-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-30 WO claimed
WO-2015200016-A1 STABILIZED MOISTURE-CURABLE POLYMERIC COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-30 WO claimed
US-5288886-A Method of preparing trialkyl-tin hydrides WITCO GMBH (DE) 1994-02-22 US claimed
EP-0068851-A1 Metallic salts of hindered phenolic anti-oxidant as anti-gel component in transition metal-catalyzed olefin polymers containing halide residue UNION CARBIDE CORPORATION (US) 1983-01-05 EP claimed
JP-63293082-A None JP disclosed
US-4009128-A Polymerization of epoxides HERCULES INCORPORATED (US) 1977-02-22 US disclosed