Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869674 | 0.88 | HSD17B10 (0.56) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL6246142 | 0.84 | ALDH1A1 (0.71) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL11919912 | 0.83 | TNKS2 (0.58) | ALDH1A1TSHRMEN1KMT2ACYP3A4 | |
| SCHEMBL20869595 | 0.80 | TSHR (0.71) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL13048294 | 0.80 | HSD17B10 (0.46) | ALDH1A1TSHRHTTCYP3A4CYP2C9 | |
| SCHEMBL28313035 | 0.79 | MAPK13 (0.53) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL11385894 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL13048284 | 0.77 | HSD17B10 (0.43) | ALDH1A1TSHRHTTCYP3A4CYP2C9 | |
| SCHEMBL20869724 | 0.74 | PTK2 (0.47) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL11068750 | 0.73 | KDM4E (0.49) | ALDH1A1TSHRMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139966-A1 | AZOLE DERIVATIVES AS WTN PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2010-12-09 | — | — | WO | disclosed |