SCHEMBL13048899

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13048925	0.88	ALDH1A1 (0.48)	CYP3A4CYP2C19CYP2C9CYP2A6NPC1
	SCHEMBL13048375	0.86	CYP3A4 (0.52)	CYP3A4CYP2C19CYP2C9CYP2A6HSD17B10
	SCHEMBL13048880	0.86	NPC1 (0.46)	CYP3A4CYP2C19CYP2C9CYP2A6NPC1
	SCHEMBL13048919	0.86	HSD17B10 (0.52)	NPC1RAB9AHSD17B10HTTALDH1A1
	SCHEMBL13048958	0.85	HTT (0.56)	CYP3A4CYP2C19NPC1RAB9AHSD17B10
	SCHEMBL17589764	0.85	CYP3A4 (0.43)	CYP3A4CYP2C19CYP2C9CYP2A6NPC1
	SCHEMBL23726147	0.85	HSD17B10 (0.48)	CYP3A4CYP2C19CYP2C9NPC1RAB9A
	SCHEMBL13048941	0.83	S1PR1 (0.52)	CYP3A4CYP2C19CYP2C9NPC1RAB9A
	SCHEMBL13048938	0.82	USP2 (0.49)	CYP3A4CYP2C19NPC1RAB9AHSD17B10
	SCHEMBL13048964	0.82	HSD17B10 (0.53)	CYP3A4CYP2C19NPC1RAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.