Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049195 | 0.86 | KMT2A (0.47) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13049193 | 0.85 | L3MBTL1 (0.63) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13399641 | 0.84 | KMT2A (0.70) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13399640 | 0.84 | KMT2A (0.63) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13399086 | 0.84 | KMT2A (0.63) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22070138 | 0.81 | KMT2A (0.61) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27405609 | 0.81 | KMT2A (0.61) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2721298 | 0.80 | CYP1A2 (0.68) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2721300 | 0.80 | CYP1A2 (0.68) | KMT2APOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30312666 | 0.80 | CTSK (0.53) | KMT2APOLBCTSKCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338643-B2 | Reagent for introduction of protein or gene | WASEDA UNIVERSITY (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | WASEDA UNIVERSITY (JP) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | C1S, SGMS1, CERT1 | KMT2A 1785/4885POLB 3728/4885CYP1A2 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.