SCHEMBL13049599

SCHEMBL13049599

Cc1cc(-c2ccc3c(c2)c2ccccc2n3CC(F)(F)F)c(C)cc1-c1ccc2c(c1)c1ccccc1n2CC(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPY5R Q15761 3/20 0.41
▸ RORA P35398 1/20 0.41
▸ RORC P51449 1/20 0.41
▸ RORB Q92753 1/20 0.41
▸ METAP2 P50579 9/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ HBB P68871 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ TSPO P30536 2/20 0.39
▸ PTGDR2 Q9Y5Y4 1/20 0.39
▸ TDO2 P48775 1/20 0.39
▸ PTGER4 P35408 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12113734 0.82 MAPT (0.58) NPY5RKDM4EMEN1ALDH1A1MAPT
SCHEMBL23148499 0.78 CYP1A2 (0.56) RORARORCRORBKDM4EALDH1A1
SCHEMBL13922000 0.77 GPR3 (0.55) NPY5RKDM4EMEN1ALDH1A1MAPT
SCHEMBL12113732 0.74 KDM4E (0.56) NPY5RKDM4EMEN1ALDH1A1MAPT
SCHEMBL13922003 0.74 MEN1 (0.51) NPY5RRORARORCRORBKDM4E
SCHEMBL23318288 0.72 KMT2A (0.44) NPY5RRORARORCRORBKDM4E
SCHEMBL15460133 0.70 ALKBH5 (0.41) NPY5RKDM4EMEN1ALDH1A1MAPT
SCHEMBL23148506 0.70 CNR2 (0.49) NPY5RRORARORCRORBKDM4E
SCHEMBL17809436 0.70 KDM4E (0.61) NPY5RKDM4EMEN1ALDH1A1MAPT
SCHEMBL13086876 0.70 NPY5R (0.56) NPY5RKDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1653784-B1 ORGANIC ELECTROLUMINESCENT DEVICE, ILLUMINATING DEVICE, AND DISPLAY KONICA MINOLTA HOLDINGS INC (JP) 2015-04-22 — — EP disclosed
EP-1464691-B1 Organic electroluminescent element, illuminator, and display KONICA MINOLTA HOLDINGS INC (JP) 2013-10-02 — — EP disclosed
US-7839075-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-23 — — US disclosed
US-7839075-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-23 — — US disclosed
US-7485376-B2 Organic electroluminescent element, illuminator, and display KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-03 — — US disclosed
US-7485376-B2 Organic electroluminescent element, illuminator, and display KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-03 — — US disclosed
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