⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856272 | 1.00 | — | — | |
| SCHEMBL131200 | 0.91 | — | — | |
| SCHEMBL134041 | 0.90 | — | — | |
| SCHEMBL134065 | 0.88 | — | — | |
| SCHEMBL2513365 | 0.83 | TK2 (0.34) | — | |
| SCHEMBL5557358 | 0.83 | TK2 (0.34) | — | |
| SCHEMBL2769069 | 0.83 | TK2 (0.34) | — | |
| SCHEMBL5856277 | 0.80 | — | — | |
| SCHEMBL5565524 | 0.80 | — | — | |
| SCHEMBL132699 | 0.74 | SLC6A11 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446412-B1 | NOVEL LNA COMPOSITIONS AND USES THEREOF | EXIQON AS (DK) | 2012-03-07 | — | — | EP | disclosed |