Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018857 | 0.81 | DPP4 (0.43) | SMN1; SMN2ALDH1A1NPSR1CA12CA14 | |
| SCHEMBL8130071 | 0.81 | DPP4 (0.43) | SMN1; SMN2ALDH1A1NPSR1CA12CA14 | |
| SCHEMBL9717667 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1NPSR1LMNAGAA | |
| SCHEMBL15368410 | 0.81 | DPP4 (0.43) | SMN1; SMN2ALDH1A1NPSR1CA12CA14 | |
| SCHEMBL14389451 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1NPSR1LMNAGAA | |
| SCHEMBL8752641 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1NPSR1LMNAGAA | |
| SCHEMBL1496401 | 0.79 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1NPSR1CYP2D6CYP2C19 | |
| SCHEMBL13049755 | 0.79 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1NPSR1CYP2D6CYP2C19 | |
| SCHEMBL13530960 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1NPSR1LMNAGAA | |
| SCHEMBL23201575 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPSR1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138791-A1 | ANTIVIRAL COMPOUNDS COMPOSED OF THREE LINKED ARYL MOIETIES TO TREAT DISEASES SUCH AS HEPATITIS C | SCHERING CORPORATION (US) | 2010-12-02 | — | — | WO | disclosed |