Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | SDCBP | O00560 | 1/20 | 0.31 |
| ▸ | SDC2 | P34741 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526954 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1NPSR1CYP2D6CYP2C19 | |
| SCHEMBL8752641 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL9717667 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL14389451 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL13049754 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPSR1CYP2D6CYP2C19 | |
| SCHEMBL1496401 | 0.77 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1NPSR1CYP2D6CYP2C19 | |
| SCHEMBL13049755 | 0.77 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1NPSR1CYP2D6CYP2C19 | |
| SCHEMBL1440450 | 0.76 | CA12 (0.38) | SMN1; SMN2ALDH1A1NPSR1CYP2C19TSHR | |
| SCHEMBL7465674 | 0.76 | LMNA (0.33) | SMN1; SMN2ALDH1A1CYP2D6CYP2C19TSHR | |
| SCHEMBL7465668 | 0.76 | LMNA (0.33) | SMN1; SMN2ALDH1A1CYP2D6CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801537-A2 | COMPOUNDS AND METHODS FOR MODULATION OF G-PROTEIN-COUPLED RECEPTORS | Primetime Life Sciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |