Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SAT1 | P21673 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361425 | 0.93 | ALDH1A1 (0.45) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5933233 | 0.86 | MAPK1 (0.43) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5933722 | 0.86 | MAPK1 (0.43) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29923169 | 0.86 | MEN1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL18354294 | 0.85 | MEN1 (0.46) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18359267 | 0.85 | MEN1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL19860988 | 0.85 | MEN1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL22800802 | 0.84 | KDM4E (0.42) | ALDH1A1GAAMEN1KMT2ATSHR | |
| SCHEMBL22800848 | 0.84 | KDM4E (0.42) | ALDH1A1GAAMEN1KMT2ATSHR | |
| SCHEMBL26516395 | 0.84 | KDM4E (0.42) | ALDH1A1GAAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297104-A1 | DENDRITIC MACROMOLECULE AND A PROCESS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297104-A1 | DENDRITIC MACROMOLECULE AND A PROCESS THEREOF | CD14, TLR3, CD40 | ALDH1A1 3319/4885GAA 3042/4885MEN1 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.