Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13050824 | 1.00 | SIGMAR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13080882 | 0.89 | SLC6A2 (0.41) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13050851 | 0.87 | HTR2A (0.52) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13050857 | 0.87 | HTR2A (0.52) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13050932 | 0.87 | HTR2A (0.52) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13050940 | 0.87 | HTR2A (0.52) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13079924 | 0.85 | SLC6A4 (0.41) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13079922 | 0.85 | SLC6A4 (0.41) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13050877 | 0.84 | HTR2A (0.55) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13050872 | 0.84 | HTR2A (0.55) | HTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292292-A1 | Treatment of Neurodegenerative Diseases Using Indatraline Analogs | LINK MEDICINE CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292292-A1 | Treatment of Neurodegenerative Diseases Using Indatraline Analogs | LINK MEDICINE CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2009036275-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES USING INDATRALINE ANALOGS | LINK MEDICINE CORPORATION (US) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292292-A1 | Treatment of Neurodegenerative Diseases Using Indatraline Analogs | HTT, SNCA, PARK7 | SIGMAR1 980/4885HTR2A 62/4885HTR2C 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.