SCHEMBL13051007

SCHEMBL13051007

C=CC(=O)OCN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.49
HCAR2 Q8TDS4 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
PTPN1 P18031 1/20 0.39
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
NCOR2 Q9Y618 2/20 0.39
CASP1 P29466 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
LMNA P02545 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL752454 0.84 THRB (0.54) THRBHCAR2L3MBTL1HDAC3HDAC1
SCHEMBL13051022 0.84 HCAR2 (0.53) THRBHCAR2L3MBTL1PTPN1CA12
SCHEMBL11313343 0.79 MAOB (0.49) THRBL3MBTL1LMNAALDH1A1POLB
SCHEMBL13051024 0.79 L3MBTL1 (0.59) THRBHCAR2L3MBTL1CA12CA9
SCHEMBL13051006 0.79 THRB (0.54) THRBHCAR2HDAC1HDAC8NPC1
SCHEMBL13051034 0.79 THRB (0.55) THRBL3MBTL1PTPN1TDP1ALDH1A1
SCHEMBL11304848 0.78 THRB (0.48) THRBL3MBTL1HDAC3HDAC1HDAC2
SCHEMBL30526404 0.77 MAOB (0.52) THRBALDH1A1
SCHEMBL34054 0.77 HCAR2 (0.65) THRBHCAR2L3MBTL1CA12CA9
Benzene SCHEMBL28307095 0.77 HCAR2 (0.65) THRBHCAR2L3MBTL1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838188-B2 Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-23 US disclosed
US-7838188-B2 Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-23 US disclosed
US-20070231720-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed
US-20070231720-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed