SCHEMBL13053014

SCHEMBL13053014

c1ccc2sc(-c3cc(-c4nc5ccccc5s4)cc(-c4nc5ccccc5s4)c3)nc2c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.69
KDM4E B2RXH2 5/20 0.69
NPC1 O15118 5/20 0.69
SMN1; SMN2 Q16637 4/20 0.69
ALDH1A1 P00352 3/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
HPGD P15428 1/20 0.69
APP P05067 5/20 0.67
MAPT P10636 4/20 0.67
LMNA P02545 2/20 0.67
GLA P06280 2/20 0.67
GAA P10253 2/20 0.67
MMP9 P14780 1/20 0.67
MMP8 P22894 1/20 0.67
NFKB1 P19838 3/20 0.66
NFKB2 Q00653 3/20 0.66
RELA Q04206 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14939305 0.98 RAB9A (0.67) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL5461064 0.92 RAB9A (0.77) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL13241652 0.91 KDM4E (0.59) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL15786286 0.91 KDM4E (0.64) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL21313421 0.91 KDM4E (0.59) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL24557199 0.91 KDM4E (0.59) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL24331861 0.91 RAB9A (0.62) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL25713615 0.91 RAB9A (0.76) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL24332358 0.90 APP (0.71) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1
SCHEMBL24331812 0.89 RAB9A (0.65) RAB9AKDM4ENPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194442-A1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER Novaled GmbH (DE) 2023-06-14 EP disclosed
EP-3406599-B1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER NOVALED GMBH (DE) 2023-02-22 EP disclosed
WO-2022080696-A1 HIGH-REFRACTIVE-INDEX BENZAZOLE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2022-04-21 WO disclosed
US-20200161559-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer NOVALED GMBH (DE) 2020-05-21 US disclosed
EP-2224790-B1 Light emitting element and azole compound UDC IRELAND LTD (IE) 2013-01-02 EP disclosed
US-7838131-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2010-11-23 US disclosed
US-7838131-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2010-11-23 US disclosed
EP-2224790-A1 Light emitting element and azole compound Fujifilm Corporation (JP) 2010-09-01 EP disclosed
US-7740956-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-7740956-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20100044638-A1 1,3,5-Tri((2-(methyl-)benzimidazol-1-yl)-)benzene; OLED'shaving a light emission maximum wavelength of 500 nm or less wherein the minimum excitation triplet energy level of the host material is higher than the minimum excitation triplet energy level of the light emitting material FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-20100044638-A1 1,3,5-Tri((2-(methyl-)benzimidazol-1-yl)-)benzene; OLED'shaving a light emission maximum wavelength of 500 nm or less wherein the minimum excitation triplet energy level of the host material is higher than the minimum excitation triplet energy level of the light emitting material FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-7632579-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2009-12-15 US disclosed
US-7632579-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2009-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200161559-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer C1S, YAP1, ESR1 RAB9A 3954/4885KDM4E 1983/4885NPC1 1989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.