Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16510392 | 0.82 | GRM2 (0.41) | GRM2GRM3DPP4ALDH1A1 | |
| SCHEMBL31603208 | 0.79 | DPP4 (0.42) | GRM2GRM3DPP4ALDH1A1OPRM1 | |
| SCHEMBL16510412 | 0.78 | GRM2 (0.42) | GRM2GRM3ALDH1A1 | |
| SCHEMBL30852824 | 0.78 | TSHR (0.45) | ALDH1A1 | |
| SCHEMBL13053320 | 0.76 | OPRM1 (0.47) | DPP4OPRM1OPRL1 | |
| SCHEMBL7926366 | 0.76 | DPP4 (0.57) | GRM2GRM3DPP4ALDH1A1OPRM1 | |
| SCHEMBL2399945 | 0.74 | OPRM1 (0.40) | GRM2GRM3DPP4ALDH1A1OPRM1 | |
| SCHEMBL8323846 | 0.74 | TSHR (0.47) | ALDH1A1 | |
| SCHEMBL24792755 | 0.73 | OPRM1 (0.47) | DPP4ALDH1A1OPRM1OPRL1 | |
| SCHEMBL24792758 | 0.73 | OPRM1 (0.47) | DPP4ALDH1A1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7837982-B2 | Imaging agents | EMORY UNIVERSITY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20070082879-A1 | Imaging Agents | EMORY UNIVERSITY (US) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082879-A1 | Imaging Agents | SLC7A1, SSTR1, SSTR3 | GRM2 699/4885GRM3 237/4885DPP4 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.