Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | OGG1 | O15527 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483328 | 0.75 | CYP3A4 (0.41) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL178747 | 0.75 | RAPGEF4 (0.36) | TTRRAPGEF4 | |
| SCHEMBL765882 | 0.73 | CYP3A4 (0.58) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL234943 | 0.73 | CYP3A4 (0.58) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL12379160 | 0.73 | TTR (0.40) | TTRRAPGEF4 | |
| SCHEMBL17481117 | 0.73 | TTR (0.40) | TTR | |
| SCHEMBL15434937 | 0.73 | TTR (0.40) | TTR | |
| SCHEMBL1314635 | 0.71 | CYP3A4 (0.55) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL27561995 | 0.71 | CYP3A4 (0.55) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL2972493 | 0.71 | CYP3A4 (0.55) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053478-B1 | Antimicrobial diaryl iodonium compositions and method | Cornell Development Group, LLC (US) | 2011-11-08 | — | — | US | disclosed |