SCHEMBL765882

SCHEMBL765882

Cc1cc(Cl)cc(C)c1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.58
CHRM1 P11229 1/20 0.58
ALOX15 P16050 1/20 0.58
MAOA P21397 1/20 0.58
TBXA2R P21731 1/20 0.58
ADRA1A P35348 1/20 0.58
HTR2B P41595 1/20 0.58
TSHR P16473 2/20 0.47
RAPGEF4 Q8WZA2 4/20 0.46
ALDH1A1 P00352 3/20 0.44
CES1 P23141 1/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
SCN4A P35499 2/20 0.35
AHR P35869 2/20 0.35
MCL1 Q07820 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9623934 0.88 CYP3A4 (0.48) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL29351204 0.84 ALDH1A1 (0.61) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL180195 0.84 ALDH1A1 (0.61) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL2670000 0.80 CYP3A4 (0.52) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL13550042 0.80 CYP3A4 (0.40) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL13550037 0.80 CYP3A4 (0.40) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL7724604 0.80 ALDH1A1 (0.56) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL234943 0.79 CYP3A4 (0.58) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL8975178 0.79 TSHR (0.47) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL1314635 0.76 CYP3A4 (0.55) CYP3A4CHRM1ALOX15MAOATBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4130100-A1 AMINE-TERMINATED POLY(ARYLENE SULFIDE) (CO)POLYMER AND ITS MANUFACTURING METHOD Solvay Specialty Polymers USA, LLC. (US) 2023-02-08 EP claimed
US-20250145770-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE TORAY INDUSTRIES, INC. (JP) 2025-05-08 US disclosed
US-20240384046-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE TORAY INDUSTRIES, INC. (JP) 2024-11-21 US disclosed
US-20240384099-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE TORAY INDUSTRIES, INC. (JP) 2024-11-21 US disclosed
CN-115335435-B Polyarylene sulfide and process for producing the same 东丽株式会社 2024-11-05 CN disclosed
US-20240287265-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE TORAY INDUSTRIES, INC. (JP) 2024-08-29 US disclosed
EP-4410897-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED PRODUCT Toray Industries, Inc. (JP) 2024-08-07 EP disclosed
EP-4410898-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE Toray Industries, Inc. (JP) 2024-08-07 EP disclosed
EP-4410895-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE Toray Industries, Inc. (JP) 2024-08-07 EP disclosed
EP-4410896-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE Toray Industries, Inc. (JP) 2024-08-07 EP disclosed
EP-1954668-B9 HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2012-03-21 EP disclosed
EP-1954668-B1 HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2011-09-28 EP disclosed
US-20100137531-A1 PROCESS FOR PRODUCING CYCLIC POLYARYLENE SULFIDE TORAY INDUSTRIES INC. (JP) 2010-06-03 US disclosed
CN-101668790-A Method for producing cyclic polyarylene sulfide TORAY INDUSTRIES 2010-03-10 CN disclosed
US-20100010058-A1 Azoline Compounds for Combating Arthropod Pests BASF SE (DE) 2010-01-14 US disclosed
EP-2116562-A1 METHOD FOR PRODUCING CYCLIC POLYARYLENE SULFIDE Toray Industries, Inc. (JP) 2009-11-11 EP disclosed
US-20080312085-A1 Pesticidal Compositions BASF SE (DE) 2008-12-18 US disclosed
US-20080312085-A1 Pesticidal Compositions BASF SE (DE) 2008-12-18 US disclosed
WO-2007147701-A1 AZOLINE COMPOUNDS FOR COMBATING ARTHROPOD PESTS BASF SE (DE) 2007-12-27 WO disclosed
WO-2007071585-A1 PESTCIDAL COMPOSITIONS BASF SE (DE) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100010058-A1 Azoline Compounds for Combating Arthropod Pests NR0B1, NR4A1, NR4A3 CYP3A4 93/4885CHRM1 155/4885ALOX15 3892/4885
US-20080312085-A1 Pesticidal Compositions ANXA1, PRDX1, PRDX2 CYP3A4 2182/4885CHRM1 95/4885ALOX15 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.