Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 9/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305888 | 0.93 | P2RX3 (0.48) | P2RX3SSTR4SSTR1PREPKDM4E | |
| SCHEMBL1305883 | 0.93 | P2RX3 (0.48) | P2RX3SSTR4SSTR1PREPKDM4E | |
| SCHEMBL1307087 | 0.91 | P2RX3 (0.49) | P2RX3PREPKDM4EALDH1A1HPGD | |
| SCHEMBL1305508 | 0.91 | P2RX3 (0.56) | P2RX3SSTR4SSTR1PREPKDM4E | |
| SCHEMBL1305513 | 0.91 | P2RX3 (0.56) | P2RX3SSTR4SSTR1PREPKDM4E | |
| SCHEMBL1306159 | 0.90 | P2RX3 (0.50) | P2RX3ALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL1305454 | 0.85 | P2RX3 (0.42) | P2RX3SSTR4SSTR1KDM4EALDH1A1 | |
| SCHEMBL1306169 | 0.84 | P2RX3 (0.51) | P2RX3PREPKDM4EALDH1A1HPGD | |
| SCHEMBL1306166 | 0.84 | P2RX3 (0.51) | P2RX3PREPKDM4EALDH1A1HPGD | |
| SCHEMBL1306645 | 0.83 | P2RX3 (0.46) | P2RX3PREPKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |