Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306169 | 0.93 | P2RX3 (0.51) | P2RX3KDM4EDRD4MEN1MAPT | |
| SCHEMBL1306166 | 0.93 | P2RX3 (0.51) | P2RX3KDM4EDRD4MEN1MAPT | |
| SCHEMBL1306472 | 0.92 | P2RX3 (0.59) | P2RX3KDM4EDRD4MEN1MAPT | |
| SCHEMBL1306465 | 0.92 | P2RX3 (0.59) | P2RX3KDM4EDRD4MEN1MAPT | |
| SCHEMBL1305453 | 0.91 | P2RX3 (0.46) | P2RX3KDM4EPREPALDH1A1HPGD | |
| SCHEMBL1306159 | 0.88 | P2RX3 (0.50) | P2RX3MEN1MAPTKMT2ATSHR | |
| SCHEMBL1307088 | 0.86 | P2RX3 (0.44) | P2RX3KDM4EDRD4MEN1MAPT | |
| SCHEMBL1305888 | 0.84 | P2RX3 (0.48) | P2RX3KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1305883 | 0.84 | P2RX3 (0.48) | P2RX3KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1307308 | 0.84 | P2RX3 (0.64) | P2RX3KDM4EDRD4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |