SCHEMBL13054876

SCHEMBL13054876

CC(C)(C)OC(=O)NC[C@H]1CN(c2ccc(-c3nc(CCl)cs3)c(F)c2)C(=O)O1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.52
F10 P00742 9/20 0.51
MAOB P27338 3/20 0.48
CALML3 P27482 2/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SDHA P31040 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3755906 0.88 MAOA (0.57) MAOAF10MAOBCALML3LMNA
SCHEMBL13054710 0.87 MAOA (0.47) MAOAF10MAOBCALML3LMNA
SCHEMBL13054709 0.87 MAOA (0.47) MAOAF10MAOBCALML3LMNA
SCHEMBL13054714 0.87 MAOA (0.47) MAOAF10MAOBCALML3LMNA
SCHEMBL14024092 0.84 MAOA (0.56) MAOAF10MAOBCALML3LMNA
SCHEMBL1224396 0.82 MAOA (0.58) MAOAF10MAOBCALML3LMNA
SCHEMBL1224398 0.82 MAOA (0.58) MAOAF10MAOBCALML3LMNA
SCHEMBL18402655 0.79 MAOA (0.55) MAOAF10MAOBCALML3LMNA
SCHEMBL2799455 0.79 MAOA (0.55) MAOAF10MAOBCALML3LMNA
SCHEMBL2799453 0.79 MAOA (0.55) MAOAF10MAOBCALML3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100298384-A1 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS DR. REDDY'S LABORATORIES LTD. (IN) 2010-11-25 US disclosed
WO-2008143649-A2 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS DR. REDDY'S LABORATORIES LIMITED (IN) 2008-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298384-A1 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS OXA1L, MIF, VIP MAOA 3034/4885F10 4714/4885MAOB 2709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.