SCHEMBL3755906

SCHEMBL3755906

O=C(O)NC[C@H]1CN(c2ccc(-c3nc(CCl)cs3)c(F)c2)C(=O)O1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.57
F10 P00742 10/20 0.50
CALML3 P27482 2/20 0.50
MAOB P27338 3/20 0.49
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SDHA P31040 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13054876 0.88 MAOA (0.52) MAOAF10CALML3MAOBLMNA
SCHEMBL3806686 0.85 MAOA (0.51) MAOAF10CALML3MAOBLMNA
SCHEMBL3747929 0.85 MAOA (0.51) MAOAF10CALML3MAOB
SCHEMBL3753109 0.85 MAOA (0.51) MAOAF10CALML3MAOBLMNA
SCHEMBL14024092 0.82 MAOA (0.56) MAOAF10CALML3MAOBLMNA
SCHEMBL1556065 0.79 MAOA (0.63) MAOAF10CALML3MAOBLMNA
SCHEMBL3753131 0.78 MAOA (0.59) MAOAF10CALML3MAOBLMNA
SCHEMBL3764737 0.78 MAOA (0.59) MAOAF10CALML3MAOBLMNA
SCHEMBL3760120 0.78 CALML3 (0.48) MAOAF10CALML3MAOB
SCHEMBL3760059 0.78 MAOA (0.47) MAOAF10CALML3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100298384-A1 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS DR. REDDY'S LABORATORIES LTD. (IN) 2010-11-25 US disclosed
WO-2008143649-A2 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS DR. REDDY'S LABORATORIES LIMITED (IN) 2008-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298384-A1 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS OXA1L, MIF, VIP MAOA 3034/4885F10 4714/4885CALML3 4408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.