SCHEMBL13055569

SCHEMBL13055569

CC1(C)c2cc3cc(-n4c5ccccc5c5ccccc54)ccc3cc2-c2cc3ccc(-n4c5ccccc5c5ccccc54)cc3cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ F2 P00734 1/20 0.33
▸ F10 P00742 1/20 0.33
▸ PRSS1 P07477 1/20 0.33
▸ GPR3 P46089 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.31
▸ RAB9A P51151 2/20 0.31
▸ GAA P10253 1/20 0.31
▸ POLB P06746 3/20 0.31
▸ PTPN1 P18031 1/20 0.31
▸ MAPK9 P45984 1/20 0.31
▸ MAPK10 P53779 1/20 0.31
▸ HTR3A P46098 1/20 0.30
▸ HDAC4 P56524 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ PMM2 O15305 1/20 0.30
▸ MPI P34949 1/20 0.30
▸ PHOSPHO1 Q8TCT1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22741294 0.97 KDM4E (0.39) KDM4EATML3MBTL1F2F10
SCHEMBL22739705 0.92 KDM4E (0.37) KDM4EATML3MBTL1F2F10
SCHEMBL17988913 0.91 KDM4E (0.36) KDM4EATML3MBTL1F2F10
SCHEMBL22739602 0.89 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL13056051 0.88 KDM4E (0.34) KDM4EATML3MBTL1F2F10
SCHEMBL22739597 0.88 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL17446022 0.88 F2 (0.32) KDM4EATML3MBTL1F2F10
SCHEMBL13056180 0.86 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL17692364 0.84 KDM4E (0.36) KDM4EATML3MBTL1F2F10
SCHEMBL14039130 0.83 KDM4E (0.44) KDM4EATML3MBTL1GPR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838130-B2 Aminodibenzofluorene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-23 — — US disclosed
US-7838130-B2 Aminodibenzofluorene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-23 — — US disclosed
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-10-29 — — US disclosed
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME L1CAM, DDC, LEF1 KDM4E 895/4885ATM 3365/4885L3MBTL1 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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