Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803375 | 0.91 | LMNA (0.53) | LMNAHSD17B10PTPN1ALDH1A1NPC1 | |
| SCHEMBL2804681 | 0.91 | LMNA (0.53) | LMNAHSD17B10PTPN1ALDH1A1NPC1 | |
| SCHEMBL2499788 | 0.89 | LMNA (0.52) | LMNAHSD17B10PTPN1ALDH1A1NPC1 | |
| SCHEMBL13311937 | 0.85 | LMNA (0.53) | LMNAHSD17B10PTPN1ALDH1A1NPC1 | |
| SCHEMBL3751031 | 0.80 | LMNA (0.41) | LMNAHSD17B10PTPN1 | |
| SCHEMBL9730908 | 0.74 | — | — | |
| SCHEMBL11001381 | 0.70 | LMNA (0.56) | LMNAHSD17B10PTPN1ALDH1A1NPC1 | |
| SCHEMBL4951420 | 0.69 | HSD17B10 (1.00) | LMNAHSD17B10PTPN1ALDH1A1NPC1 | |
| SCHEMBL25357317 | 0.67 | LMNA (0.34) | LMNAHSD17B10PTPN1ALDH1A1NPC1 | |
| SCHEMBL9678981 | 0.67 | TSHR (0.42) | LMNAHSD17B10PTPN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012391-B2 | Organic compounds | GIVAUDAN SA (CH) | 2015-04-21 | — | — | US | disclosed |
| US-20100292128-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292128-A1 | Organic Compounds | TRPA1, FASN, OR10J3 | LMNA 1886/4885HSD17B10 47/4885PTPN1 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.