Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10151903 | 0.93 | SMN1; SMN2 (0.38) | POLBALOX15MGAMGAASI | |
| SCHEMBL1306329 | 0.92 | ALOX15 (0.41) | POLBALOX15MGAMGAASI | |
| Bromide SCHEMBL1494095 | 0.90 | ALOX15 (0.39) | POLBALOX15MGAMGAASI | |
| Hydrochloric Acid SCHEMBL755483 | 0.90 | ALOX15 (0.39) | POLBALOX15MGAMGAASI | |
| SCHEMBL24189316 | 0.85 | POLB (0.43) | POLBALOX15MGAMGAASI | |
| SCHEMBL25408248 | 0.85 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL18075817 | 0.83 | SMN1; SMN2 (0.39) | POLBALOX15MGAMGAASI | |
| SCHEMBL1493761 | 0.83 | MGAM (0.39) | POLBALOX15MGAMGAASI | |
| SCHEMBL22640209 | 0.83 | POLB (0.44) | POLBALOX15MGAMGAASI | |
| SCHEMBL17893420 | 0.83 | ALDH1A1 (0.46) | POLBALOX15MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175043-A1 | PYRIDOPYRIMIDINE DERIVATIVE AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-08-29 | — | — | WO | disclosed |
| EP-1712547-B1 | BICYCLOESTER DERIVATIVE | KYORIN SEIYAKU KK (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-8053465-B2 | Bicycloester derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2011-11-08 | — | — | US | disclosed |
| US-7754757-B2 | Bicycloester derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20100093825-A1 | Bicycloester derivative | FUKUDA YASUMICHI | 2010-04-15 | — | — | US | disclosed |
| US-20080146818-A1 | Dipeptidylpeptidase IV (DPP-IV) inhibitory activity; (2S,4S)-1-[[N-(4-ethoxycarbonylbicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile)); diabetes | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-06-19 | — | — | US | disclosed |
| EP-1712547-A1 | BICYCLOESTER DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2006-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093825-A1 | Bicycloester derivative | DPP4, DPP7, DPP3 | POLB 3346/4885ALOX15 4054/4885MGAM 367/4885 |
| US-20080146818-A1 | Dipeptidylpeptidase IV (DPP-IV) inhibitory activity; (2S,4S)-1-[[N-(4-ethoxycarbonylbicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile)); diabetes | DPP4, DPP7, DPP3 | POLB 2825/4885ALOX15 3548/4885MGAM 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.