SCHEMBL130569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL129356	0.97	PDE4A (0.59)	PDE4APDE4BPDE4DPDE4CNPY1R
	SCHEMBL5704271	0.95	PDE4A (0.57)	PDE4APDE4BPDE4DPDE4CNPY1R
	SCHEMBL29340248	0.93	NPY1R (0.49)	PDE4APDE4BPDE4DPDE4CNPY1R
	SCHEMBL31096114	0.93	PDE4A (0.50)	PDE4APDE4BPDE4DPDE4CNPY1R
	SCHEMBL133005	0.93	PDE4A (0.50)	PDE4APDE4BPDE4DPDE4CNPY1R
	SCHEMBL21823754	0.85	PDE4A (0.44)	PDE4APDE4BPDE4DPDE4C
	SCHEMBL31096321	0.85	PDE4A (0.44)	PDE4APDE4BPDE4DPDE4C
	SCHEMBL682835	0.84	KDM4E (0.44)	PDE4APDE4D
	SCHEMBL128455	0.83	NPY1R (0.50)	PDE4DNPY1RNPY2RPOLB
	SCHEMBL705028	0.82	POLB (0.57)	PDE4BNPY1RNPY2RPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.