Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 6/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21823754 | 1.00 | PDE4A (0.44) | PDE4AFPR2PDE4BSLC6A4PDE4D | |
| SCHEMBL31096050 | 0.91 | PDE4B (0.53) | PDE4AFPR2PDE4BSLC6A4HTR6 | |
| SCHEMBL21823664 | 0.91 | PDE4B (0.53) | PDE4AFPR2PDE4BSLC6A4HTR6 | |
| SCHEMBL133005 | 0.89 | PDE4A (0.50) | PDE4APDE4BSLC6A4PDE4DPDE4C | |
| SCHEMBL31096114 | 0.89 | PDE4A (0.50) | PDE4APDE4BSLC6A4PDE4DPDE4C | |
| SCHEMBL129356 | 0.85 | PDE4A (0.59) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL130569 | 0.85 | PDE4A (0.55) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL5704271 | 0.84 | PDE4A (0.57) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL682835 | 0.80 | KDM4E (0.44) | PDE4ASLC6A4PDE4D | |
| SCHEMBL29340248 | 0.79 | NPY1R (0.49) | PDE4APDE4BSLC6A4PDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166177-B | Boron-containing PDE4 inhibitors | 辉瑞公司 | 2024-09-03 | — | — | CN | disclosed |