Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 4/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844926 | 0.81 | KMT2A (0.58) | CHRM4CYP3A4KMT2ACDK7CDK9 | |
| SCHEMBL28151054 | 0.79 | BCL6 (0.50) | CHRM4CYP3A4KMT2ACDK7CDK9 | |
| SCHEMBL13057434 | 0.77 | IRAK1 (0.41) | CHRM4CYP3A4 | |
| SCHEMBL4186011 | 0.76 | GABBR2 (0.43) | GABBR2GABBR1CHRM4CYP3A4KMT2A | |
| SCHEMBL993784 | 0.75 | KMT2A (0.64) | KMT2APDE10A | |
| SCHEMBL1934159 | 0.75 | KMT2A (0.69) | KMT2APDE10APDE4A | |
| SCHEMBL8546608 | 0.75 | LRRK2 (0.50) | JAK2 | |
| SCHEMBL3119338 | 0.75 | CRHR1 (0.59) | GABBR2GABBR1CRHR1 | |
| SCHEMBL1937546 | 0.74 | KMT2A (0.71) | KMT2APDE10APDE4A | |
| SCHEMBL24435731 | 0.73 | GABBR2 (0.50) | GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759356-B2 | Compounds and methods for controlling fungi | DOW AGROSCIENCES, LLC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20100298143-A1 | COMPOUNDS AND METHODS FOR CONTROLLING FUNGI | DOW AGROSCIENCES LLC (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298143-A1 | COMPOUNDS AND METHODS FOR CONTROLLING FUNGI | C5, CBR3, CBR1 | GABBR2 469/4885GABBR1 279/4885CHRM4 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.