Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13710044 | 0.95 | GPR119 (0.33) | GPR119CHRM5CHRM1 | |
| SCHEMBL13003158 | 0.93 | GPR119 (0.33) | GPR119CHRM5CHRM1 | |
| SCHEMBL13003157 | 0.93 | GPR119 (0.33) | GPR119CHRM5CHRM1 | |
| SCHEMBL532246 | 0.85 | CHRM5 (0.37) | GPR119CHRM5CHRM1 | |
| SCHEMBL532381 | 0.82 | CHRM5 (0.39) | GPR119CHRM5CHRM1 | |
| SCHEMBL13003093 | 0.77 | CHRM5 (0.35) | CHRM5CHRM1 | |
| SCHEMBL13497405 | 0.76 | CHRM5 (0.34) | GPR119CHRM5CHRM1 | |
| SCHEMBL13003113 | 0.76 | ABCG2 (0.35) | CHRM5CHRM1 | |
| SCHEMBL532241 | 0.73 | MAPT (0.38) | CHRM5CHRM1 | |
| Trifluoroacetic Acid SCHEMBL3421525 | 0.70 | CHRM5 (0.35) | CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851606-B2 | Negatively charged minor groove binders | ELITECH HOLDING B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | PCNA, NCL, HNRNPH3 | GPR119 3972/4885CHRM5 3722/4885CHRM1 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.