Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532381 | 0.97 | CHRM5 (0.39) | CHRM5CHRM1ALDH1A1LMNAMAPT | |
| SCHEMBL13003158 | 0.92 | GPR119 (0.33) | CHRM5CHRM1ALDH1A1LMNAMAPT | |
| SCHEMBL13003157 | 0.92 | GPR119 (0.33) | CHRM5CHRM1ALDH1A1LMNAMAPT | |
| SCHEMBL13497405 | 0.88 | CHRM5 (0.34) | CHRM5CHRM1MAPTKCNJ1KCNH2 | |
| SCHEMBL532241 | 0.85 | MAPT (0.38) | CHRM5CHRM1LMNAMAPTKCNJ1 | |
| SCHEMBL13060247 | 0.85 | GPR119 (0.30) | CHRM5CHRM1GPR119 | |
| SCHEMBL13710044 | 0.84 | GPR119 (0.33) | CHRM5CHRM1GPR119DHODH | |
| SCHEMBL13003093 | 0.83 | CHRM5 (0.35) | CHRM5CHRM1LMNAMAPTKCNJ1 | |
| Trifluoroacetic Acid SCHEMBL3421525 | 0.83 | CHRM5 (0.35) | CHRM5CHRM1LMNAMAPTKCNJ1 | |
| SCHEMBL13252825 | 0.81 | CHRM5 (0.40) | CHRM5CHRM1ALDH1A1KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430147-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-1235938-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| US-20060292589-A1 | Oligonucleotide probes containing two labels useful in hybridization assays | EPOCH BIOSCIENCES, INC. (US) | 2006-12-28 | — | — | US | disclosed |
| US-20040191796-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| US-20040081959-A9 | Using oligonucleotide detectors; hybridization analyzing | EPOCH BIOSCIENCES, INC. (US) | 2004-04-29 | — | — | US | disclosed |
| US-6727356-B1 | AS PROBES SUCH AS FOR FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHER INCLUDES A 4-(PHENYLDIAZENYL)PHENYLAMINE STRUCTURE; IMPROVED SIGNAL TO NOISE RATIO AND HYBRIDIZATION | EPOCH PHARMACEUTICALS, INC. | 2004-04-27 | — | — | US | disclosed |
| US-6699975-B2 | OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION | EPOCH BIOSCIENCES, INC. | 2004-03-02 | — | — | US | disclosed |
| US-6653473-B2 | Nucleotide sequences for use as diagnostic tool in genetic analysis | EPOCH BIOSCIENCES, INC. | 2003-11-25 | — | — | US | disclosed |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | EPOCH BIOSCIENCES, INC. (US) | 2003-05-22 | — | — | US | disclosed |
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | EPOCH BIOSCIENCES, INC. (US) | 2003-01-09 | — | — | US | disclosed |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | CHRM5 4256/4885CHRM1 4835/4885ALDH1A1 2350/4885 |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | CHRM5 4248/4885CHRM1 4847/4885ALDH1A1 2211/4885 |
| US-20040081959-A9 | Using oligonucleotide detectors; hybridization analyzing | DCLRE1B, DDX21, DDX41 | CHRM5 4449/4885CHRM1 4834/4885ALDH1A1 3725/4885 |
| US-20060292589-A1 | Oligonucleotide probes containing two labels useful in hybridization assays | DCLRE1B, DDX21, DCLRE1A | CHRM5 4630/4885CHRM1 4872/4885ALDH1A1 3246/4885 |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | IPO4, PTBP3, DDX5 | CHRM5 1118/4885CHRM1 2078/4885ALDH1A1 3183/4885 |
| US-20040191796-A1 | Fluorescent quenching detection reagents and methods | DDX5, IPO4, DBF4 | CHRM5 1172/4885CHRM1 2380/4885ALDH1A1 3333/4885 |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | DCLRE1B, SNRPE, ZFR | CHRM5 4309/4885CHRM1 4722/4885ALDH1A1 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.