SCHEMBL13060359

SCHEMBL13060359

CC(S)c1ncc(C=O)n1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4039693 0.85 SMN1; SMN2 (0.41) TRIM24TRIM33ALDH1A1
SCHEMBL13060581 0.74 KMT2A (0.32) ALDH1A1
SCHEMBL858846 0.70
SCHEMBL5808029 0.69 ALDH1A1 (0.39) TRIM24TRIM33ALDH1A1
SCHEMBL3533339 0.68
SCHEMBL12232255 0.68
SCHEMBL13060549 0.67 ALDH1A1 (0.40) ALDH1A1
SCHEMBL15201281 0.66 TYR (0.43) ALDH1A1
SCHEMBL1778393 0.65 TRIM24 (0.36) TRIM24TRIM33ALDH1A1
SCHEMBL18153538 0.65 ALDH1A1 (0.39) TRIM24TRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846956-B2 Malononitrile compound as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-07 US disclosed
US-20090149425-A1 Malononitrile compound as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-11 US disclosed
EP-1704143-B1 MALONONITRILE COMPOUND AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2008-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149425-A1 Malononitrile compound as pesticides NR0B1, RTN4, OR10J3 TRIM24 1073/4885TRIM33 548/4885ALDH1A1 2751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.