Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061102 | 0.86 | CALM1 (0.64) | CALM1CAMKK2DRD1OPRK1OPRM1 | |
| SCHEMBL13005720 | 0.84 | OPRK1 (0.49) | CALM1CAMKK2DRD2DRD3DRD1 | |
| SCHEMBL13061026 | 0.82 | TAAR1 (0.57) | CALM1CAMKK2 | |
| SCHEMBL13060692 | 0.82 | TAAR1 (0.57) | CALM1CAMKK2OPRM1MEN1KMT2A | |
| SCHEMBL13061011 | 0.82 | TAAR1 (0.57) | CALM1CAMKK2MEN1KMT2A | |
| SCHEMBL13061128 | 0.80 | BCHE (0.47) | CALM1CAMKK2OPRK1OPRM1OPRD1 | |
| SCHEMBL13061028 | 0.79 | CYP1A2 (0.57) | CALM1CAMKK2MEN1KMT2A | |
| SCHEMBL13061027 | 0.79 | CALM1 (0.47) | CALM1CAMKK2DRD2DRD3MEN1 | |
| SCHEMBL13060710 | 0.79 | CALM1 (0.77) | CALM1CAMKK2MEN1KMT2AHSD17B2 | |
| SCHEMBL13061030 | 0.79 | CALM1 (0.47) | CALM1CAMKK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |