Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11982417 | 0.92 | CCKBR (0.52) | CCKBRTRPV1CHRM1 | |
| SCHEMBL2264164 | 0.92 | CCKBR (0.52) | CCKBRTRPV1CHRM1 | |
| SCHEMBL13061378 | 0.91 | TRPV1 (0.40) | CCKBRTRPV1 | |
| SCHEMBL11982409 | 0.90 | TRPV1 (0.44) | CCKBRTRPV1 | |
| SCHEMBL13061384 | 0.89 | CCKBR (0.39) | CCKBRTRPV1 | |
| SCHEMBL11982454 | 0.86 | CCKBR (0.48) | CCKBRTRPV1CHRM1 | |
| SCHEMBL11982408 | 0.82 | CCKBR (0.49) | CCKBRTRPV1 | |
| SCHEMBL13061379 | 0.81 | TRPV1 (0.46) | CCKBRTRPV1 | |
| SCHEMBL12390483 | 0.81 | TRPV1 (0.55) | CCKBRTRPV1CHRM1 | |
| SCHEMBL13061375 | 0.81 | CCKBR (0.54) | CCKBRTRPV1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289498-A1 | Compositions And Methods Relating To Novel Compounds And Targets Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-11-15 | — | — | US | disclosed |
| US-7851465-B2 | Compositions and methods relating to novel compounds and targets thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-12-14 | — | — | US | disclosed |
| US-20080269194-A1 | Compositions And Methods Relating To Novel Compounds And Targets Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269194-A1 | Compositions And Methods Relating To Novel Compounds And Targets Thereof | BAX, BAD, BAK1 | CCKBR 416/4885TRPV1 364/4885CHRM1 2574/4885 |
| US-20120289498-A1 | Compositions And Methods Relating To Novel Compounds And Targets Thereof | BAX, BAD, BAK1 | CCKBR 416/4885TRPV1 364/4885CHRM1 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.