Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12390481 | 0.92 | CCKBR (0.48) | CCKBRTRPV1 | |
| SCHEMBL13061376 | 0.89 | CCKBR (0.42) | CCKBRTRPV1 | |
| SCHEMBL13061378 | 0.89 | TRPV1 (0.40) | CCKBRTRPV1HDAC1 | |
| SCHEMBL13618700 | 0.82 | TRPV1 (0.51) | CCKBRTRPV1 | |
| SCHEMBL2264164 | 0.81 | CCKBR (0.52) | CCKBRTRPV1 | |
| SCHEMBL11982417 | 0.81 | CCKBR (0.52) | CCKBRTRPV1 | |
| SCHEMBL11982408 | 0.81 | CCKBR (0.49) | CCKBRTRPV1 | |
| SCHEMBL12390474 | 0.80 | CCKBR (0.50) | CCKBRTRPV1 | |
| SCHEMBL13061379 | 0.80 | TRPV1 (0.46) | CCKBRTRPV1 | |
| SCHEMBL11982409 | 0.79 | TRPV1 (0.44) | CCKBRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851465-B2 | Compositions and methods relating to novel compounds and targets thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-12-14 | — | — | US | disclosed |