Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376695 | 0.84 | EP300 (0.45) | EP300TSHRGRIK1F7F3 | |
| SCHEMBL28958488 | 0.81 | POLB (0.44) | EP300TSHRGRIK1ALDH1A1POLB | |
| SCHEMBL22199302 | 0.81 | EP300 (0.35) | EP300TSHRGRIK1F7F3 | |
| SCHEMBL1782422 | 0.80 | ALDH1A1 (0.43) | EP300TSHRGRIK1F7F3 | |
| SCHEMBL1782421 | 0.80 | ALDH1A1 (0.43) | EP300TSHRGRIK1F7F3 | |
| SCHEMBL13025501 | 0.78 | GRIK1 (0.43) | EP300TSHRGRIK1F7F3 | |
| SCHEMBL10385774 | 0.78 | EP300 (0.53) | EP300F7F3ALDH1A1TDP1 | |
| SCHEMBL10385775 | 0.78 | EP300 (0.53) | EP300F7F3ALDH1A1TDP1 | |
| SCHEMBL11406196 | 0.77 | TSHR (0.39) | EP300TSHRGRIK1ALDH1A1CCR2 | |
| SCHEMBL11406195 | 0.77 | TSHR (0.39) | EP300TSHRGRIK1ALDH1A1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317085-A1 | CO-INCUBATING CONFINED MICROBIAL COMMUNITIES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-12-16 | — | — | US | disclosed |