SCHEMBL28958488

SCHEMBL28958488

CCCCC=C(C)CC(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
POLA1 P09884 1/20 0.44
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
EP300 Q09472 1/20 0.38
EPHX2 P34913 1/20 0.38
TSHR P16473 4/20 0.38
CA12 O43570 2/20 0.37
CA14 Q9ULX7 2/20 0.37
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
GRIK1 P39086 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
ALOX5 P09917 1/20 0.35
OXER1 Q8TDS5 1/20 0.35
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28118393 0.82 TSHR (0.38) POLBPOLA1EP300TSHRALDH1A1
SCHEMBL13061577 0.81 EP300 (0.42) POLBEP300TSHRALDH1A1GRIK1
SCHEMBL29376695 0.79 EP300 (0.45) POLBEP300TSHRALDH1A1LMNA
SCHEMBL14314040 0.79 MGAM (0.50) POLBPOLA1MGAMGAASI
SCHEMBL19605717 0.78 EPHX2 (0.41) POLBPOLA1MGAMGAASI
SCHEMBL7949305 0.77 LMNA (0.50) POLBPOLA1EPHX2TSHRCA12
SCHEMBL7951003 0.77 LMNA (0.50) POLBPOLA1EPHX2TSHRCA12
SCHEMBL7949308 0.77 LMNA (0.50) POLBPOLA1EPHX2TSHRCA12
SCHEMBL16021161 0.77 LMNA (0.54) POLBPOLA1EP300EPHX2TSHR
SCHEMBL11577022 0.74 ALDH1A1 (0.56) POLBPOLA1EPHX2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262642-A Method for extracting and purifying volatile oil of Caryopteris clandonensis and application thereof 河南省医药科学研究院 2022-04-01 CN disclosed