Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.66 |
| ▸ | PGR | P06401 | 6/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062170 | 0.88 | AR (0.50) | ARPGRNR3C2NR3C1CYP3A4 | |
| SCHEMBL12949430 | 0.86 | PGR (0.67) | ARPGRNR3C2NR3C1CYP3A4 | |
| SCHEMBL12949722 | 0.86 | PGR (0.67) | ARPGRNR3C2NR3C1CYP3A4 | |
| SCHEMBL13062189 | 0.85 | AR (0.67) | ARPGRNR3C2NR3C1CYP3A4 | |
| SCHEMBL13770467 | 0.85 | AR (0.48) | ARPGRNR3C2NR3C1CYP3A4 | |
| SCHEMBL13557252 | 0.81 | AR (0.57) | ARPGRNR3C2NR3C1CYP3A4 | |
| SCHEMBL13013797 | 0.79 | AR (1.00) | ARPGRNR3C2 | |
| SCHEMBL13013564 | 0.79 | AR (1.00) | ARPGRNR3C2 | |
| SCHEMBL12942706 | 0.79 | AR (0.55) | ARPGRNR3C2NR3C1CHRM2 | |
| SCHEMBL12942779 | 0.79 | AR (0.55) | ARPGRNR3C2NR3C1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317632-A1 | 17-(1'PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317632-A1 | 17-(1'PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | NR5A1, CYP19A1, CYP17A1 | AR 44/4885PGR 8/4885NR3C2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.