Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062187 | 0.85 | AR (0.66) | ARPGRNR3C2NR3C1CHRM2 | |
| SCHEMBL13062170 | 0.85 | AR (0.50) | ARPGRNR3C2NR3C1CHRM2 | |
| SCHEMBL13013605 | 0.80 | AR (0.75) | ARPGRNR3C2PDK1PDK2 | |
| SCHEMBL12904813 | 0.72 | AR (0.49) | ARPGRNR3C2PDK1PDK2 | |
| SCHEMBL12949722 | 0.71 | PGR (0.67) | ARPGRNR3C2NR3C1CHRM2 | |
| SCHEMBL12949430 | 0.71 | PGR (0.67) | ARPGRNR3C2NR3C1CHRM2 | |
| SCHEMBL13062189 | 0.71 | AR (0.67) | ARPGRNR3C2NR3C1MEN1 | |
| SCHEMBL13062450 | 0.71 | AR (0.52) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13013660 | 0.70 | AR (0.77) | ARPGRNR3C2NR3C1 | |
| SCHEMBL12942942 | 0.70 | PGR (0.52) | ARPGRNR3C2PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083268-A2 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |