Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 7/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31481612 | 0.82 | GPR84 (0.54) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL3131647 | 0.82 | GPR84 (0.54) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL916811 | 0.75 | GPR84 (0.47) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL5496842 | 0.75 | CSNK2A1 (0.55) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL15984707 | 0.75 | TYR (0.50) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL398920 | 0.75 | CSNK2A1 (0.60) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL397084 | 0.75 | CSNK2A1 (0.55) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL394578 | 0.75 | GPR84 (0.69) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL25594837 | 0.75 | CSNK2A1 (0.55) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL8527499 | 0.75 | CSNK2A1 (0.60) | GPR84CSNK2A1AHRCYP2A6NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331344-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2010054138-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331344-A1 | Modulators of ATP-Binding Cassette Transporters | CFTR, ABCB1, ABCC2 | GPR84 409/4885CSNK2A1 4288/4885AHR 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.